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Valine

Other name(s):

a-amino-isovaleric acid

Unsubstantiated claims

There may be benefits that have not yet been proven through research.

Valine may help treat malnutrition due to drug addiction.

Recommended intake

Amino acids (AAs) can be taken as single AAs or in AA combinations. They also come as part of multi-vitamins, proteins, and food supplements. The forms include tablets, fluids, and powders.

If you eat enough protein in your diet, you get all of the amino acids you need.

You should take valine supplements with leucine and isoleucine.

There are no conditions that increase how much valine you need.

Side effects, toxicity, and interactions

Valine is 1 of the branch-chain amino acids. These amino acids help make energy and cholesterol. Using a single amino acid supplement may lead to negative nitrogen balance. This can lessen how well your metabolism works. It can also make your kidneys work harder. In children, taking single amino acid supplements may also cause growth problems.

You should not take high doses of single amino acids for long periods of time.

Women who are pregnant or breastfeeding shouldn’t use valine supplements. You should not use them if you have maple syrup urine disease (MSUD). This is a rare, inherited disorder.

Online Medical Reviewer: Cynthia Godsey
Online Medical Reviewer: Diane Horowitz MD
Online Medical Reviewer: Rita Sather RN
Date Last Reviewed: 1/1/2019
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