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Methylphenidate Hydrochloride Oral capsule, biphasic release

What is this medicine?

METHYLPHENIDATE(meth il FEN i date) is used to treat attention-deficit hyperactivity disorder (ADHD).

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not crush, cut, or chew the capsule. You may take this medicine with food. Take your medicine at regular intervals. Do not take it more often than directed. If you take your medicine more than once a day, try to take your last dose at least 8 hours before bedtime. This well help prevent the medicine from interfering with your sleep.

If you have difficulty swallowing, the capsule may be opened and the contents gently sprinkled on a small amount (1 tablespoon) of cool applesauce. Do not sprinkle on warm applesauce or this may result in improper dosing. The contents of the capsule should not be crushed or chewed. Take the medicine immediately after sprinkling on the cool applesauce. Do not store for future use. Drink a glass of water, milk or juice after taking the sprinkles with applesauce.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years for selected conditions, precautions do apply.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • anxiety or severe nervousness

  • chest pain

  • fast, irregular heartbeat

  • fever, or hot, dry skin

  • high blood pressure

  • males: prolonged or painful erection

  • uncontrollable head, mouth, neck, arm, or leg movements

  • unusual bleeding or bruising

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • weight loss

  • headache

  • mild stomach upset

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • atomoxetine

  • lithium

  • medicines called MAO Inhibitors like Nardil, Parnate, Marplan, Eldepryl

  • other stimulant medicines like amphetamine, dextroamphetamine, dexmethylphenidate, modafinil

  • procarbazine

This medicine may also interact with the following medications:

  • medicines for blood pressure

  • caffeine

  • medicines to decrease appetite or cause weight loss

  • medicines for depression, anxiety, or psychotic disturbances

  • medicines for seizures

  • warfarin

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Keep container tightly closed. Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • difficulty swallowing, problems with the esophagus, or a history of blockage of the stomach or intestines

  • family history of suicide

  • glaucoma

  • heart condition or recent history of a heart attack

  • high blood pressure

  • history of a drug or alcohol abuse problem

  • liver disease

  • mental illness, including anxiety, bipolar disorder, depression, mania or schizophrenia

  • motor tics, family history or diagnosis of Tourette's syndrome

  • overactive thyroid

  • seizures

  • taken an MAOI like Carbex, Eldepryl, Marplan, Nardil, or Parnate in last 14 days

  • an unusual or allergic reaction to methylphenidate, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. This prescription requires that you follow special procedures with your doctor and pharmacy. You will need to have a new written prescription from your doctor or health care professional every time you need a refill.

This medicine may affect your concentration, or hide signs of tiredness. Until you know how this drug affects you, do not drive, ride a bicycle, use machinery, or do anything that needs mental alertness. If you are having trouble sleeping, and this continues to be a regular and bothersome side effect, contact your health care provider to discuss your options.

Tell your doctor or health care professional if this medicine loses its effects, or if you feel you need to take more than the prescribed amount. Do not change the dosage without talking to your doctor or health care professional. Do not suddenly stop your medicine. Ask your doctor or health care professional for advice.

For males, contact your doctor or health care professional right away if you have an erection that lasts longer than 4 hours or if it becomes painful. This may be a sign of a serious problem and must be treated right away to prevent permanent damage.

Decreased appetite is a common side effect when starting this medicine. Eating small, frequent meals or snacks can help. Talk to your doctor if you continue to have poor eating habits. Height and weight growth of a child taking this medicine will be monitored closely.

If you are scheduled for any surgery, tell your healthcare provider that you are taking this medicine. You may need to stop taking this medicine before the procedure.

Tell your doctor or healthcare professional right away if you notice unexplained wounds on your fingers and toes while taking this medicine. You should also tell your healthcare provider if you experience numbness or pain, changes in the skin color, or sensitivity to temperature in your fingers or toes.

Online Medical Reviewer: Louise Akin, RN, BSN
Online Medical Reviewer: Daphne Pierce-Smith, RN, MSN, FNP, CCRC
Last Review Date: 12/17/2013
© 2000-2014 Krames StayWell, 780 Township Line Road, Yardley, PA 19067. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.

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