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You are here: Home > Health A to Z > Acid mucopolysaccharides



Acid mucopolysaccharides

Definition
How the test will feel
Alternative Names
Why the test is performed
How the test is performed
Normal Values
How to prepare for the test
What abnormal results mean


Urine sample
Urine sample

 Definition  

Acid mucopolysaccharides is a test that measures the amount of mucopolysaccharides released into the urine over a 24-hour period. Mucopolysaccharides are long chains of sugar molecules found throughout the body, often in mucus and in fluid around the joints.

 Alternative Names  

AMP; Dermatan sulfate - urine; Urine heparan sulfate; Urine dermatan sulfate; Heparan sulfate - urine

 How the test is performed  

A 24-hour urine sample is needed.

  • On day 1, urinate into the toilet when you get up in the morning.
  • Afterwards, collect all urine in a special container for the next 24 hours. Keep it in the refrigerator or a cool place during the collection period.
  • On day 2, urinate into the container when you get up in the morning.
  • Cap the container. Label the container with your name, the date, the time of completion, and deliver it to the laboratory or your health care provider as soon as possible.

 How to prepare for the test  

There is no special preparation needed.

 How the test will feel  

The test involves only normal urination, and there is no discomfort.

 Why the test is performed  

This test is done to diagnose a rare group of genetic disorders called mucopolysaccharidoses, including Hurler syndrome. These disorders involve a build up of mucopolysaccharides in body tissue.

This test is usually only done in infants who have a family history of MPS.

 Normal Values  

Normal levels vary with age and from lab to lab.

 What abnormal results mean  

Abnormally high levels are a sign of mucopolysaccharidosis. Further tests are needed to determine the specific type of mucopolysaccharidosis.

Review date: 5/27/2007

Reviewed By: Daniel R Alexander, MD, Department of Internal Medicine, St. Mary's Hospital, Leonardtown, MD. Review provided by VeriMed Healthcare Network.

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