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Cinacalcet tablets

What is this medicine?

CINACALCET (sin a CAL set) is used to treat patients with chronic kidney disease who are on dialysis. It is also used to treat high levels of calcium in the blood of patients with certain parathyroid gland problems.

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Do not break, chew, or crush tablets. Take this medicine with food or right after a meal. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on your doctor's advice.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • depressed mood

  • signs and symptoms of a dangerous change in heartbeat or heart rhythm like chest pain; dizziness; fast or irregular heartbeat; palpitations; feeling faint or lightheaded, falls; breathing problems

  • signs and symptoms of bleeding such as bloody or black, tarry stools; spitting up blood or brown material that looks like coffee grounds

  • signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired

  • signs and symptoms of low calcium like fast heartbeat, muscle cramps or muscle pain; pain, tingling, numbness in the hands or feet; seizures

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • bone pain

  • diarrhea

  • joint pain

  • loss of appetite

  • nausea, vomiting

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • thioridazine

This medicine may also interact with the following medications:

  • erythromycin

  • flecainide

  • grapefruit juice

  • medicines for depression, anxiety, or psychotic disturbances

  • medicines for fungal infections like fluconazole, itraconazole, ketoconazole, voriconazole

  • medicines for pain

  • medicines for sleep

  • St. John's wort

  • vinblastine

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • heart disease

  • history of irregular heartbeat

  • liver disease

  • low levels of calcium in the blood

  • seizures

  • stomach or intestine problems

  • an unusual or allergic reaction to cinacalcet, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

What should I watch for while using this medicine?

Visit your doctor for regular checks on your progress. Your doctor will order important blood tests while you are taking this medicine. This medicine may cause an increase or decrease in your blood pressure. Check your blood pressure as directed. Ask your doctor or health care professional what your blood pressure should be and when you should contact him or her.

This medicine alters the calcium level in your blood. You may need to be on a special diet. Talk to your health care provider about the foods you eat and the vitamins you take.

NOTE:This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. Copyright© 2018 Elsevier
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